Viewing Reports

Just-DNA-Seq makes a set of reports on a genome which contain data about longevity-related gene variants, known cancer risks and drug responses.

Opening Reports

  1. Go to the Reports page.

  2. In the Longevity Combined section, click Download.

  3. When asked by your web browser what to do with the report file, open it in the browser. The report will be opened on a new tab.

  4. Switch to the report tab in your browser.

Part 1: Longevity Significant Variations

This report contains gene variants which have significant influence on longevity. It has the following columns:

+ - clicking this green button opens detailed information on each entry (row), and the button becomes red with a - sign. Clicking this - closes the details. Clicking + in the header opens the details for all rows and behaves in the same way (clicking - in the header closes all detail sections).

RSID - the reference sequence ID of the variant.

Population - population(s) on which the research was conducted, e.g. Greek, Ashkenazi Jewish etc., or multiple (for more details, open +).

Gene - gene the variant belongs to.

Your Genotype - which variants your genome contains. Note that in case of homozygosity two letters should be the same, and for heterozygosity they differ.

Ref allele - the reference allele.

Alt allele - the alternative allele.

Zygosity - hom (homozygosity) or het (heterozygosity).

Weight - weight of this variant (the degree of significance).

Part 2: Cancer Report

This report shows variants with known cancer risks and contains the following columns:

+ - acting the same way in all reports (see above).

# - the number of an entry (row).

Chrom - chromosome the variant belongs to, e.g. chr1.

Position - position of the variant on the chromosome (number).

Gene - gene the variant belongs to, like in the previous report.

RSID - the reference sequence ID of the variant.

cDNA Change - change in the coding DNA by the variant.

Zygosity - hom or het (see above).

Allele Frequency - frequency of the allele.

Phenotype Name - description of condition(s) associated with the variant.

Significance - description of significance of this variant.

Part 3: Drugs Report

This report contains known issues of response to certain drugs associated with gene variants. It has the following columns:

# - the number of an entry (row).

Variant/Haplotypes - by rsID.

Drug(s) - name(s) of drug(s) response to which is affected by the variants.

Phenotype Category: Efficacy, Dosage, or Other.

Significance - yes or no.

Sentence - description of the case.

Allele Of Frequency In Cases - allele of the variant (one or more letters A, T, C or G) in cases involved.

Allele Of Frequency In Controls - allele of the variant in controls.

Ratio Stat Type - the ratio statistics type.

Effect - information on the effect.

Note: In some browsers the last one or two columns may be found beyond the visible area at 100% zoom level; in such cases try zooming out to 90%, 80% and so on, until everything is visible.